The reactivity of N-[(2-oxoindolin-3-ylidene)-2-oxiacetyl] amino acids
نویسندگان
چکیده
منابع مشابه
3-Amino-N′-(2-oxoindolin-3-ylidene)benzohydrazide
The title compound, C(15)H(12)N(4)O(2), contains two substituted benzohydrazide and indole rings linked via a C=N double bond. The dihedral angle between the benzene ring and the indole ring system is 11.38 (10)°. The mol-ecular structure is stabilized by an intra-molecular N-H⋯O hydrogen bond, forming a six-membered ring. The crystal structure is consolidated by inter-molecular N-H⋯O and C-H⋯O...
متن کاملSynthesis, Characterization, and Anti-Cancer Activity of Some New N'-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives.
Eight novel N'-(2-oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazone derivatives 4a-h were synthesized and fully characterized by IR, NMR ((1)H-NMR and (13)C-NMR), elemental analysis, and X-ray crystallography. The cyto-toxicity and in vitro anti-cancer evaluation of the prepared compounds have been assessed against two different human tumour cell lines including human liver (HepG2) and ...
متن کامل2-(4-Isobutylphenyl)-N′-[(3Z)-2-oxoindolin-3-ylidene]propanohydrazide
In the title compound, C(21)H(23)N(3)O(2), the indolin-2-one group is essentially planar, with a maximum deviation of 0.016 (2) Å for the N atom, and makes a dihedral angle of 84.38 (14)° with the benzene ring. The =N-N(H)-C(=O)-C- torsion angle is 0.9 (3)°. In the crystal, mol-ecules are linked into a three-dimensional network via N-H⋯O and C-H⋯O hydrogen bonds. In addition, a C-H⋯π inter-acti...
متن کامل(Z)-2-(5-Methyl-2-oxoindolin-3-ylidene)-N-phenylhydrazinecarbothioamide
In the title compound, C(16)H(14)N(4)OS, the dihedral angle between the nine-membered 5-methyl-indolin-2-one ring system and the benzene ring is 10.21 (7)°. Intra-molecular cyclic N-H⋯O and C-H⋯S hydrogen-bonding inter-actions [graph set S(6)] are present within the N-N-C-N chain between the ring systems. In the crystal, mol-ecules form centrosymmetric cyclic dimers through pairs of N-H⋯O hydro...
متن کامل(Z)-2-(5-Chloro-2-oxoindolin-3-ylidene)-N-methylhydrazinecarbothioamide
In the title compound, C(10)H(9)ClN(4)OS, an intra-molecular N-H⋯O hydrogen-bonding inter-action and an N-H⋯N inter-action generate ring motifs [graph sets S(6) and S(5), respectively]. In the crystal, mol-ecules form a chain through N-H⋯O hydrogen bonds, and these are extended by N-H⋯S hydrogen-bonding inter-actions into an infinite three-dimensional network. The crystal structure also exhibit...
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ژورنال
عنوان ژورنال: Vìsnik farmacìï
سال: 2015
ISSN: 2415-8844,1562-7241
DOI: 10.24959/nphj.15.2050